ENAT Study Enhancing Nutrition Enhancing Nutrition and Antenatal Infection Treatment for Maternal and Child Health

Funding Agency Date Range
Bill and Melinda Gates Foundation (BMGF), Child Investment Fund Foundation (CIFF) January 2018 –> 2021

Project Summary (Objective & activities) 

This project aims to determine the incremental impact of a combined package of antenatal maternal infection and nutrition interventions on fetal growth and birth size, above that of a nutrition intervention package alone. If substantial gains in birth size are demonstrated, this trial will provide the evidence for the scale-up of combined ANC packages that include both maternal nutrition and infection management, in Ethiopia and beyond.

Cluster randomized controlled trial will be implemented to determine the impact of a package of WHO-recommended antenatal care interventions to enhance maternal nutritional status and manage maternal pregnancy infections on infant size at birth.


Primary Aim: To determine if the provision of a package of interventions that address maternal infections and nutrition during pregnancy to women in rural communities of Ethiopia can increase infant birth weight by at least 75 grams and infant birth length by at least 0.5 centimeters, compared to provision of a package that includes the nutrition support interventions.


Secondary Aims: To determine if provision of a package of interventions for maternal infections and nutrition support during pregnancy to women in rural communities of Ethiopia can:

  • Increase mean length of gestation
  • Reduce the prevalence of low birth weight, small-for-gestational age, and preterm birth
  • Increase maternal weight gain
  • Reduce maternal anemia and parasitemia
  • Increase Z-scores for infant length-for-age, weight for length, weight-for-age at 6 months of age

 Sub-Aim: To determine the impact of the ANC strengthening on ANC coverage and facility based delivery rates.


Working on the budget breakdown and activity timeline. Drafting the pre and rapid assessment tools.Identifying undergoing interventions through communicating with governmental and other non-governmental organizations.

Contact Information

ACIPH Building, Yeka Subcity
Ayat Zone 8,  YK_13_4064
House number B227_23
P.O. Box 26751/100




Mon – Fri 9:00A.M. – 5:00P.M.

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